When it comes to weight loss medications, most of the conversation focuses on women. But men make up a significant and growing percentage of patients using GLP-1 receptor agonists — and the results are impressive.
In the STEP clinical trials for Semaglutide, male participants lost an average of 14.7% of their body weight, closely mirroring the overall trial results. Men tend to lose weight faster in the initial months due to higher baseline metabolic rates and greater lean muscle mass.
Men face unique challenges with obesity that go beyond aesthetics. Visceral fat — the deep abdominal fat that wraps around organs — is more common in men and is strongly linked to cardiovascular disease, insulin resistance, and elevated blood pressure. GLP-1 medications have been shown to specifically reduce visceral fat stores.
The cardiovascular benefits are particularly relevant for men. The SELECT trial demonstrated a 20% reduction in major cardiovascular events (heart attack, stroke, and cardiovascular death) with Semaglutide. Given that heart disease is the leading cause of death in American men, this is a significant finding.
Testosterone levels often improve as men lose weight. Excess body fat converts testosterone to estrogen through a process called aromatization. As fat mass decreases, many men see natural improvements in testosterone levels, energy, mood, and even libido.
At Precision Weight + Wellness, we see men across all age groups and activity levels. Whether you’re a former athlete who’s gained weight over the years, a busy professional who can’t find time to exercise, or someone dealing with metabolic issues — the program is designed to work with your specific situation.
One common concern men raise is muscle loss during weight loss. Our program addresses this through nutritional guidance that prioritizes protein intake, exercise recommendations that emphasize resistance training, and careful monitoring of body composition — not just scale weight.
If you’re a man considering medical weight management, know that you’re not alone and this isn’t a ‘women’s program.’ The science works the same way. Schedule a consultation with our medical team to discuss your goals and explore your options.